GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27

GATA4 is expressed in the proximal 85% of small intestine where it promotes a proximal intestinal (‘jejunal’) identity while repressing a distal intestinal (‘ileal’) identity, but its molecular mechanisms are unclear. Here, we tested the hypothesis that GATA4 promotes a jejunal vs. ileal identity in...

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Bibliografske podrobnosti
izdano v:Biochim Biophys Acta
Main Authors: Aronson, B. E., Aronson, S. Rabello, Berkhout, R. P., Chavoushi, S. F., He, A., Pu, W. T., Verzi, M. P., Krasinski, S. D.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684644/
https://ncbi.nlm.nih.gov/pubmed/24878542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.05.018
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