Histone H4 lysine 20 acetylation is associated with gene repression in human cells

Histone acetylation is generally associated with gene activation and chromatin decondensation. Recent mass spectrometry analysis has revealed that histone H4 lysine 20, a major methylation site, can also be acetylated. To understand the function of H4 lysine 20 acetylation (H4K20ac), we have develop...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kaimori, Jun-Ya, Maehara, Kazumitsu, Hayashi-Takanaka, Yoko, Harada, Akihito, Fukuda, Masafumi, Yamamoto, Satoko, Ichimaru, Naotsugu, Umehara, Takashi, Yokoyama, Shigeyuki, Matsuda, Ryo, Ikura, Tsuyoshi, Nagao, Koji, Obuse, Chikashi, Nozaki, Naohito, Takahara, Shiro, Takao, Toshifumi, Ohkawa, Yasuyuki, Kimura, Hiroshi, Isaka, Yoshitaka
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827026/
https://ncbi.nlm.nih.gov/pubmed/27064113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24318
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