Histone H4 lysine 20 acetylation is associated with gene repression in human cells

Histone acetylation is generally associated with gene activation and chromatin decondensation. Recent mass spectrometry analysis has revealed that histone H4 lysine 20, a major methylation site, can also be acetylated. To understand the function of H4 lysine 20 acetylation (H4K20ac), we have develop...

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Publicado no:Sci Rep
Main Authors: Kaimori, Jun-Ya, Maehara, Kazumitsu, Hayashi-Takanaka, Yoko, Harada, Akihito, Fukuda, Masafumi, Yamamoto, Satoko, Ichimaru, Naotsugu, Umehara, Takashi, Yokoyama, Shigeyuki, Matsuda, Ryo, Ikura, Tsuyoshi, Nagao, Koji, Obuse, Chikashi, Nozaki, Naohito, Takahara, Shiro, Takao, Toshifumi, Ohkawa, Yasuyuki, Kimura, Hiroshi, Isaka, Yoshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827026/
https://ncbi.nlm.nih.gov/pubmed/27064113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24318
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