A kinetic model for amyloid formation in the prion diseases: importance of seeding.
The transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases characterized by amyloid formation in the brain. The major amyloid protein is the prion protein (PrP). PrP and the beta-amyloid protein of Alzheimer disease share a similar sequence that, in both cases, may be respon...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5959 |
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