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A kinetic model for amyloid formation in the prion diseases: importance of seeding.

The transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases characterized by amyloid formation in the brain. The major amyloid protein is the prion protein (PrP). PrP and the beta-amyloid protein of Alzheimer disease share a similar sequence that, in both cases, may be respon...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Come, J H, Fraser, P E, Lansbury, P T
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1993
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5959
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