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Canonical transient receptor potential 3 channels activate NF-κB to mediate allergic airway disease via PKC-α/IκB-α and calcineurin/IκB-β pathways

The purpose of this study was to determine the role of canonical transient receptor potential 3 (TRPC3) channel in allergen-induced airway disease (AIAD) and its underlying signaling mechanisms. The procedures included (1) intravenous injection of lentiviral TRPC3 channel or nonsilencing short hairp...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Song, Tengyao, Zheng, Yun-Min, Vincent, Peter A., Cai, Dongsheng, Rosenberg, Paul, Wang, Yong-Xiao
Format: Artigo
Langue:Inglês
Publié: Federation of American Societies for Experimental Biology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684550/
https://ncbi.nlm.nih.gov/pubmed/26373801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-274860
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