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Differential submitochondrial localization of PINK1 as a molecular switch for mediating distinct mitochondrial signalling pathways

Mutations in mitochondrial kinase PINK1 cause Parkinson disease (PD), but the submitochondrial site(s) of PINK1 action remains unclear. Here, we report that three-dimensional structured illumination microscopy (3D-SIM) enables super-resolution imaging of protein submitochondrial localization. Dual-c...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Fallaize, Dana, Chin, Lih-Shen, Li, Lian
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684445/
https://ncbi.nlm.nih.gov/pubmed/26436374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.09.020
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