EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

Epithelial renewal in the Drosophila intestine is orchestrated by Intestinal Stem Cells (ISCs). Following damage or stress the intestinal epithelium produces ligands that activate the epidermal growth factor receptor (EGFR) in ISCs. This promotes their growth and division and, thereby, epithelial re...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Jin, Yinhua, Ha, Nati, Forés, Marta, Xiang, Jinyi, Gläßer, Christine, Maldera, Julieta, Jiménez, Gerardo, Edgar, Bruce A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684324/
https://ncbi.nlm.nih.gov/pubmed/26683696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005634
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