EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

Epithelial renewal in the Drosophila intestine is orchestrated by Intestinal Stem Cells (ISCs). Following damage or stress the intestinal epithelium produces ligands that activate the epidermal growth factor receptor (EGFR) in ISCs. This promotes their growth and division and, thereby, epithelial re...

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Publicado en:PLoS Genet
Main Authors: Jin, Yinhua, Ha, Nati, Forés, Marta, Xiang, Jinyi, Gläßer, Christine, Maldera, Julieta, Jiménez, Gerardo, Edgar, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684324/
https://ncbi.nlm.nih.gov/pubmed/26683696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005634
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