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A Two-Day Continuous Nicotine Infusion Is Sufficient to Demonstrate Nicotine Withdrawal in Rats as Measured Using Intracranial Self-Stimulation

Avoidance of the negative affective (emotional) symptoms of nicotine withdrawal (e.g., anhedonia, anxiety) contributes to tobacco addiction. Establishing the minimal nicotine exposure conditions required to demonstrate negative affective withdrawal signs in animals, as well as understanding moderato...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Muelken, Peter, Schmidt, Clare E., Shelley, David, Tally, Laura, Harris, Andrew C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684239/
https://ncbi.nlm.nih.gov/pubmed/26658557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144553
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