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Chemistry with an Artificial Primer of Polyhydroxybutyrate Synthase Suggests a Mechanism for Chain Termination

[Image: see text] Polyhydroxybutyrate (PHB) synthases (PhaCs) catalyze the conversion of 3-(R)-hydroxybutyryl CoA (HBCoA) to PHB, which is deposited as granules in the cytoplasm of microorganisms. The class I PhaC from Caulobacter crescentus (PhaC(Cc)) is a highly soluble protein with a turnover num...

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Pubblicato in:Biochemistry
Autori principali: Buckley, Rachael M., Stubbe, JoAnne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2015
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684083/
https://ncbi.nlm.nih.gov/pubmed/25741756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501405b
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