Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent

There is established clinical evidence for differences in drug response, cure rates and survival outcomes between different ethnic populations, but the causes are poorly understood. Differences in frequencies of functional genetic variants in key drug response and metabolism genes may significantly...

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Bibliografiske detaljer
Udgivet i:Pharmacogenomics J
Main Authors: Aminkeng, F, Ross, CJD, Rassekh, SR, Brunham, LR, Sistonen, J, Dube, M-P, Ibrahim, M, Nyambo, TB, Omar, SA, Froment, A, Bodo, J-M, Tishkoff, S, Carleton, BC, Hayden, MR
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684079/
https://ncbi.nlm.nih.gov/pubmed/23588107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2013.13
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