Network Characteristic Analysis of ADR-related Proteins and Identification of ADR-ADR Associations

Adverse drug reactions (ADRs) are caused by interactions between drugs or their metabolites and specific proteins. Knowledge of these proteins is important for facilitating mechanistic research of ADRs and new drug discovery. Here, we identified 41 network modules from an ADR-protein network; analys...

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Main Authors: Chen, Xiujie, Liu, Xiangqiong, Jia, Xiaodong, Tan, Fujian, Yang, Ruizhi, Chen, Sheng, Liu, Lei, Wang, Yunfeng, Chen, Yuelong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638162/
https://ncbi.nlm.nih.gov/pubmed/23625301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01744
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