Insulin–InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages

The lineage commitment of HSCs generates balanced myeloid and lymphoid populations in hematopoiesis. However, the underlying mechanisms that control this process remain largely unknown. Here, we show that insulin–insulin receptor (InsR) signaling is required for lineage commitment of multipotent pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Xia, Pengyan, Wang, Shuo, Du, Ying, Huang, Guanling, Satoh, Takashi, Akira, Shizuo, Fan, Zusen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2015
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683997/
https://ncbi.nlm.nih.gov/pubmed/26573296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150618
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