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Insulin–InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages
The lineage commitment of HSCs generates balanced myeloid and lymphoid populations in hematopoiesis. However, the underlying mechanisms that control this process remain largely unknown. Here, we show that insulin–insulin receptor (InsR) signaling is required for lineage commitment of multipotent pro...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Exp Med |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Rockefeller University Press
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683997/ https://ncbi.nlm.nih.gov/pubmed/26573296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150618 |
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