Forkhead Box P1 (FOXP1) Transcription Factor Regulates Hepatic Glucose Homeostasis

Dysregulation of hepatic gluconeogenesis contributes to the pathogenesis of diabetes, yet the detailed molecular mechanisms remain to be fully elucidated. Here we show that FOXP1, a transcriptional repressor, plays a key role in the regulation of systemic glucose homeostasis. Hepatic expression leve...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zou, Yongkang, Gong, Ning, Cui, Ying, Wang, Xiaojuan, Cui, Anfang, Chen, Qi, Jiao, Tao, Dong, Xueyu, Yang, Hao, Zhang, Shutian, Fang, Fude, Chang, Yongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683280/
https://ncbi.nlm.nih.gov/pubmed/26504089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681627
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