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An Essential Role of the Forkhead-Box Transcription Factor Foxo1 in Control of T Cell Homeostasis and Tolerance
Members of the Forkhead box O (Foxo) family of transcription factors are key regulators of cellular responses, but their function in the immune system remains incompletely understood. Here we show that T cell-specific deletion of Foxo1 gene in mice led to spontaneous T cell activation, effector T ce...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692529/ https://ncbi.nlm.nih.gov/pubmed/19285438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.02.003 |
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