Llwytho...

An Essential Role of the Forkhead-Box Transcription Factor Foxo1 in Control of T Cell Homeostasis and Tolerance

Members of the Forkhead box O (Foxo) family of transcription factors are key regulators of cellular responses, but their function in the immune system remains incompletely understood. Here we show that T cell-specific deletion of Foxo1 gene in mice led to spontaneous T cell activation, effector T ce...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ouyang, Weiming, Beckett, Omar, Flavell, Richard A., Li, Ming O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692529/
https://ncbi.nlm.nih.gov/pubmed/19285438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.02.003
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!