Store-operated Ca(2+) Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells

Store-operated Ca(2+) channels (SOCs) are voltage-independent Ca(2+) channels activated upon depletion of the endoplasmic reticulum Ca(2+) stores. Early studies suggest the contribution of such channels to Ca(2+) homeostasis in insulin-secreting pancreatic β-cells. However, their composition and con...

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發表在:J Biol Chem
Main Authors: Sabourin, Jessica, Le Gal, Loïc, Saurwein, Lisa, Haefliger, Jacques-Antoine, Raddatz, Eric, Allagnat, Florent
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2015
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683273/
https://ncbi.nlm.nih.gov/pubmed/26494622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682583
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