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Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca(2+) Channels: NEW TARGETS OF ALDOSTERONE IN CARDIOMYOCYTES

Store-operated Ca(2+) entry (SOCE) has emerged as an important mechanism in cardiac pathology. However, the signals that up-regulate SOCE in the heart remain unexplored. Clinical trials have emphasized the beneficial role of mineralocorticoid receptor (MR) signaling blockade in heart failure and ass...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sabourin, Jessica, Bartoli, Fiona, Antigny, Fabrice, Gomez, Ana Maria, Benitah, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933247/
https://ncbi.nlm.nih.gov/pubmed/27129253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693911
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