Loading...
Carboxyl-terminal Truncations of ClC-Kb Abolish Channel Activation by Barttin Via Modified Common Gating and Trafficking
ClC-K chloride channels are crucial for auditory transduction and urine concentration. Mutations in CLCNKB, the gene encoding the renal chloride channel hClC-Kb, cause Bartter syndrome type III, a human genetic condition characterized by polyuria, hypokalemia, and alkalosis. In recent years, several...
Na minha lista:
| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683263/ https://ncbi.nlm.nih.gov/pubmed/26453302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675827 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|