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Reduced Membrane Insertion of CLC-K by V33L Barttin Results in Loss of Hearing, but Leaves Kidney Function Intact

In the mammalian ear, transduction of sound stimuli is initiated by K(+) entry through mechano-sensitive channels into inner hair cells. K(+) entry is driven by a positive endocochlear potential that is maintained by the marginal cell layer of the stria vascularis. This process requires basolateral...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Tan, Hua, Bungert-Plümke, Stefanie, Fahlke, Christoph, Stölting, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430073/
https://ncbi.nlm.nih.gov/pubmed/28555110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00269
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