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miR-346 Up-regulates Argonaute 2 (AGO2) Protein Expression to Augment the Activity of Other MicroRNAs (miRNAs) and Contributes to Cervical Cancer Cell Malignancy

MicroRNAs (miRNAs) are a class of post-transcriptional regulators of gene expression, and AGO2 is essential for miRNA activity. In this study, we focused on the regulation of AGO2 by miR-346 and the consequences in cervical cancer cells. miR-346 enhanced the expression of AGO2, resulting in the incr...

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Vydáno v:J Biol Chem
Hlavní autoři: Guo, Junfei, Lv, Jing, Liu, Min, Tang, Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683258/
https://ncbi.nlm.nih.gov/pubmed/26518874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691857
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