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Conversion of MyoD to a neurogenic factor: binding site specificity determines lineage
MyoD and NeuroD2, master regulators of myogenesis and neurogenesis, bind to a “shared” E-box sequence (CAGCTG) and a “private” sequence (CAGGTG or CAGATG, respectively). To determine whether private-site recognition is sufficient to confer lineage specification, we generated a MyoD mutant with the D...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683018/ https://ncbi.nlm.nih.gov/pubmed/25801030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.055 |
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