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Comparison of endogenous and overexpressed MyoD shows enhanced binding of physiologically bound sites

BACKGROUND: Transcription factor overexpression is common in biological experiments and transcription factor amplification is associated with many cancers, yet few studies have directly compared the DNA-binding profiles of endogenous versus overexpressed transcription factors. METHODS: We analyzed M...

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Autori principali: Yao, Zizhen, Fong, Abraham P, Cao, Yi, Ruzzo, Walter L, Gentleman, Robert C, Tapscott, Stephen J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666993/
https://ncbi.nlm.nih.gov/pubmed/23566431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-3-8
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