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Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation

Most transcription factor families contain highly related paralogs generated by gene duplication and functional divergence is generally accomplished by activation of distinct sets of genes by each member. Here we compare the molecular functions of Myf5 and MyoD, two highly related bHLH transcription...

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Библиографические подробности
Опубликовано в: :Dev Cell
Главные авторы: Conerly, Melissa L., Yao, Zizhen, Zhong, Jun Wen, Groudine, Mark, Tapscott, Stephen J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769793/
https://ncbi.nlm.nih.gov/pubmed/26906734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.01.021
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