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Methods to Determine the Lagrangian Shear Experienced by Platelets during Thrombus Growth

Platelets can become activated in response to changes in flow-induced shear; however, the underlying molecular mechanisms are not clearly understood. Here we present new techniques for experimentally measuring the flow-induced shear rate experienced by platelets prior to adhering to a thrombus. We e...

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Pubblicato in:PLoS One
Autori principali: Pinar, Isaac P., Arthur, Jane F., Andrews, Robert K., Gardiner, Elizabeth E., Ryan, Kris, Carberry, Josie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682839/
https://ncbi.nlm.nih.gov/pubmed/26660525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144860
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