Can Lean Body Mass Be Used to Reduce the Dose of Heparin and Protamine for Obese Patients Undergoing Cardiopulmonary Bypass?

Increasing numbers of obese patients are presenting for cardiac surgery. The convention for heparin dose dictates that a bolus of 300 IU heparin per kilogram of total body weight (TBW) is administered before CPB. During CPB, the activated clotting time (ACT) is maintained for longer than 480 seconds...

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Pubblicato in:J Extra Corpor Technol
Autori principali: Baker, Mya S., Skoyles, Julian R., Shajar, Matt, Skinner, Henry, Richens, David, Mitchell, Ian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of ExtraCorporeal Technology 2005
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Scientific Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682530/
https://ncbi.nlm.nih.gov/pubmed/16117451
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