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Heparin-protamine balance after neonatal cardiopulmonary bypass surgery

BACKGROUND: Neonates undergoing cardiopulmonary bypass (CPB) are at risk for excessive bleeding. Blood is anticoagulated with heparin during CPB. Heparin activity is reversed with protamine at the end of CPB. Paradoxically, protamine also inhibits blood coagulation when it is dosed in excess of hepa...

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Bibliografski detalji
Izdano u:J Thromb Haemost
Glavni autori: Peterson, J.A., Maroney, S.A., Zwifelhofer, W., Wood, J.P., Yan, K., Bercovitz, R.S., Woods, R.K., Mast, A.E.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173634/
https://ncbi.nlm.nih.gov/pubmed/30016577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14245
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