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Heparin-protamine balance after neonatal cardiopulmonary bypass surgery
BACKGROUND: Neonates undergoing cardiopulmonary bypass (CPB) are at risk for excessive bleeding. Blood is anticoagulated with heparin during CPB. Heparin activity is reversed with protamine at the end of CPB. Paradoxically, protamine also inhibits blood coagulation when it is dosed in excess of hepa...
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| Publicado no: | J Thromb Haemost |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173634/ https://ncbi.nlm.nih.gov/pubmed/30016577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14245 |
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