A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

BACKGROUND: Computational methods for T cell-based vaccine target discovery focus on selection of highly conserved peptides identified across pathogen variants, followed by prediction of their binding of human leukocyte antigen molecules. However, experimental studies have shown that T cells often t...

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Bibliografiske detaljer
Udgivet i:BMC Med Genomics
Main Authors: Olsen, Lars R, Simon, Christian, Kudahl, Ulrich J, Bagger, Frederik O, Winther, Ole, Reinherz, Ellis L, Zhang, Guang L, Brusic, Vladimir
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682376/
https://ncbi.nlm.nih.gov/pubmed/26679766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-8-S4-S1
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