A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

BACKGROUND: Computational methods for T cell-based vaccine target discovery focus on selection of highly conserved peptides identified across pathogen variants, followed by prediction of their binding of human leukocyte antigen molecules. However, experimental studies have shown that T cells often t...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Olsen, Lars R, Simon, Christian, Kudahl, Ulrich J, Bagger, Frederik O, Winther, Ole, Reinherz, Ellis L, Zhang, Guang L, Brusic, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682376/
https://ncbi.nlm.nih.gov/pubmed/26679766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-8-S4-S1
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