A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding

BACKGROUND: Computational methods for T cell-based vaccine target discovery focus on selection of highly conserved peptides identified across pathogen variants, followed by prediction of their binding of human leukocyte antigen molecules. However, experimental studies have shown that T cells often t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Med Genomics
Prif Awduron: Olsen, Lars R, Simon, Christian, Kudahl, Ulrich J, Bagger, Frederik O, Winther, Ole, Reinherz, Ellis L, Zhang, Guang L, Brusic, Vladimir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682376/
https://ncbi.nlm.nih.gov/pubmed/26679766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-8-S4-S1
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