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RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome

Down syndrome is the most common chromosomal disorder affecting the nervous system in humans. To date, investigations of neural anomalies in Down syndrome have focused on the central nervous system, although dysfunction of the peripheral nervous system is a common manifestation. The molecular and ce...

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Publicat a:Nat Commun
Autors principals: Patel, Ami, Yamashita, Naoya, Ascaño, Maria, Bodmer, Daniel, Boehm, Erica, Bodkin-Clarke, Chantal, Ryu, Yun Kyoung, Kuruvilla, Rejji
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682116/
https://ncbi.nlm.nih.gov/pubmed/26658127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10119
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