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RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome

Down syndrome is the most common chromosomal disorder affecting the nervous system in humans. To date, investigations of neural anomalies in Down syndrome have focused on the central nervous system, although dysfunction of the peripheral nervous system is a common manifestation. The molecular and ce...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Patel, Ami, Yamashita, Naoya, Ascaño, Maria, Bodmer, Daniel, Boehm, Erica, Bodkin-Clarke, Chantal, Ryu, Yun Kyoung, Kuruvilla, Rejji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682116/
https://ncbi.nlm.nih.gov/pubmed/26658127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10119
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