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Use of functional polymorphisms to elucidate the peptide binding site of TAP complexes
The transporter associated with antigen processing (TAP) translocates peptides from the cytosol to the endoplasmic reticulum (ER) lumen to enable immune surveillance by CD8(+) T cells. Peptide transport is preceded by peptide binding to a cytosol-accessible surface of TAP1/TAP2 complexes, but the lo...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681580/ https://ncbi.nlm.nih.gov/pubmed/26324772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500985 |
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