Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells

Atypical teratoid/rhabdoid tumors (ATRT) are rare, highly malignant, embryonal CNS tumors with a poor prognosis. Therapy relies on highly toxic chemotherapy and radiotherapy. To improve outcomes and decrease morbidity, more targeted therapy is required. Gene expression analysis revealed elevated exp...

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Publicado en:J Neurooncol
Main Authors: Venkataraman, Sujatha, Alimova, Irina, Tello, Tiffany, Harris, Peter S., Knipstein, Jeffrey A., Donson, Andrew M., Foreman, Nicholas K., Liu, Arthur K., Vibhakar, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681522/
https://ncbi.nlm.nih.gov/pubmed/22246202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0795-y
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