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Electrophysiological analysis of mammalian cells expressing hERG using automated 384-well-patch-clamp
BACKGROUND: An in vitro electrophysiological assay system, which can assess compound effects and thus show cardiotoxicity including arrhythmia risks of test drugs, is an essential method in the field of drug development and toxicology. METHODS: In this study, high-throughput electrophysiological rec...
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| Publicado no: | BMC Pharmacol Toxicol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4681162/ https://ncbi.nlm.nih.gov/pubmed/26671227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-015-0042-9 |
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