Long-lived Plasma Cells Are Contained Within the CD19(−)CD38(hi)CD138(+) Subset in Human Bone Marrow

Antibody responses to viral infections are sustained for decades by long-lived plasma cells (LLPCs). However, LLPCs have yet to be characterized in humans. Here we used CD19, CD38, and CD138 to identify four PC subsets in human bone marrow (BM). We found that the CD19(−)CD38(hi)CD138(+) subset was m...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Halliley, Jessica L., Tipton, Christopher, Liesveld, Jane, Rosenberg, Alexander F., Darce, Jaime, Gregoretti, Ivan V., Popova, Lana, Kaminiski, Denise, Fucile, Christopher F., Albizua-Santin, Igor, Kyu, Shuya, Chiang, Kuang-Yueh, Bradley, Kyle T., Burack, Richard, Slifka, Mark, Hammarlund, Erika, Wu, Hao, Zhao, Liping, Walsh, Edward E., Falsey, Ann R., Randall, Troy D., Cheung, Wan Cheung, Sanz, Iñaki, Lee, F. Eun-Hyung
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680845/
https://ncbi.nlm.nih.gov/pubmed/26187412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.06.016
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