Human CD38(hi)CD138(+) Plasma Cells Can Be Generated In Vitro from CD40-Activated Switched-Memory B Lymphocytes

B lymphocyte differentiation into long-lived plasma cells is the keystone event for the production of long-term protective antibodies. CD40-CD154 and CD27-CD70 interactions are involved in human B lymphocyte differentiation into CD38(hi)CD138(+) cells in vivo as well as in vitro. In this study, we h...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Itoua Maïga, Rayelle, Bonnaure, Guillaume, Tremblay Rochette, Josiane, Néron, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352507/
https://ncbi.nlm.nih.gov/pubmed/25759831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/635108
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