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Influence of Cardiopulmonary Bypass on the Interaction of Recombinant Factor VIIa with Activated Platelets

Recombinant factor VIIa (rFVIIa) interacts preferentially with coated platelets characterized by a high exposure of phosphatidyl serine (PS), FV, FVIII, FIX, and FX binding, and fibrinogen. Cardiopulmonary bypass (CPB) is known to impair platelet function. In this study, the influence of CPB on form...

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Bibliografiske detaljer
Udgivet i:J Extra Corpor Technol
Main Authors: Kjalke, Marianne, Runge, Marx, Rojkjaer, Rasmus, Steinbruchel, Daniel, Johansson, Pär I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of ExtraCorporeal Technology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680214/
https://ncbi.nlm.nih.gov/pubmed/19681308
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