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Influence of Cardiopulmonary Bypass on the Interaction of Recombinant Factor VIIa with Activated Platelets

Recombinant factor VIIa (rFVIIa) interacts preferentially with coated platelets characterized by a high exposure of phosphatidyl serine (PS), FV, FVIII, FIX, and FX binding, and fibrinogen. Cardiopulmonary bypass (CPB) is known to impair platelet function. In this study, the influence of CPB on form...

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Библиографические подробности
Опубликовано в: :J Extra Corpor Technol
Главные авторы: Kjalke, Marianne, Runge, Marx, Rojkjaer, Rasmus, Steinbruchel, Daniel, Johansson, Pär I.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of ExtraCorporeal Technology 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680214/
https://ncbi.nlm.nih.gov/pubmed/19681308
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