The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells

OBJECTIVE: Cancer stem cells (CSCs) represent the root of many solid cancers including pancreatic ductal adenocarcinoma, are highly chemoresistant and represent the cellular source for disease relapse. However the mechanisms involved in these processes still need to be fully elucidated. Understandin...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Cioffi, Michele, Trabulo, Sara M, Sanchez-Ripoll, Yolanda, Miranda-Lorenzo, Irene, Lonardo, Enza, Dorado, Jorge, Reis Vieira, Catarina, Ramirez, Juan Carlos, Hidalgo, Manuel, Aicher, Alexandra, Hahn, Stephan, Sainz, Bruno, Heeschen, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4680182/
https://ncbi.nlm.nih.gov/pubmed/25887381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308470
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