Glutamine deprivation counteracts hypoxia-induced chemoresistance

The microenvironment of solid tumors is a key determinant of therapy efficacy. The co-occurrence of oxygen and nutrient deprivation is a common phenomenon of the tumor microenvironment and associated with treatment resistance. Cholangiocarcinoma (CCA) is characterized by a very poor prognosis and pr...

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Bibliografske podrobnosti
izdano v:Neoplasia
Main Authors: Wappler, Jessica, Arts, Martijn, Röth, Anjali, Heeren, Ron M.A., Peter Neumann, Ulf, Olde Damink, Steven W., Soons, Zita, Cramer, Thorsten
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press 2019
Teme:
Original article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883317/
https://ncbi.nlm.nih.gov/pubmed/31765939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.10.004
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