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A Novel Mechanism of pH Buffering in C. elegans Glia: Bicarbonate Transport via the Voltage-Gated ClC Cl(−) Channel CLH-1

An important function of glia is the maintenance of the ionic composition and pH of the synaptic microenvironment. In terms of pH regulation, HCO(3)(−) buffering has been shown to be important in both glia and neurons. Here, we used in vivo fluorescent pH imaging and RNA sequencing of the amphid she...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Grant, Jeff, Matthewman, Cristina, Bianchi, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679820/
https://ncbi.nlm.nih.gov/pubmed/26674864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3237-15.2015
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