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The voltage-dependent ClC-2 chloride channel has a dual gating mechanism
Functional and structural studies demonstrate that Cl(−) channels of the ClC family have a dimeric double-barrelled structure, with each monomer contributing an identical pore. Single protopore gating is a fast process dependent on Cl(−) interaction within the selectivity filter and in ClC-0 has a l...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664870/ https://ncbi.nlm.nih.gov/pubmed/14724195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.060046 |
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