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Effect of an N-terminus deletion on voltage-dependent gating of the ClC-2 chloride channel
ClC-2, a chloride channel widely expressed in mammalian tissues, is activated by hyperpolarisation and extracellular acidification. Deletion of amino acids 16–61 in rat ClC-2 abolishes voltage and pH dependence in two-electrode voltage-clamp experiments in amphibian oocytes. These results have been...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290594/ https://ncbi.nlm.nih.gov/pubmed/12381811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.026096 |
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