Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells

The mechanisms by which some melanoma cells adapt to BRAF inhibitor therapy are incompletely understood. In the present study, we used mass spectrometry-based phosphoproteomics to determine how BRAF inhibition remodeled the signaling network of melanoma cell lines that were BRAF-mutant and PTEN-null...

詳細記述

保存先:
書誌詳細
出版年:Oncogene
主要な著者: Fedorenko, Inna V., Abel, Ethan V., Koomen, John M., Fang, Bin, Wood, Elizabeth R., Chen, Y. Ann, Fisher, Kate J., Iyengar, Sanjana, Dahlman, Kimberly B., Wargo, Jennifer A., Flaherty, Keith T., Sosman, Jeffrey A., Sondak, Vernon K., Messina, Jane L., Gibney, Geoffrey T., Smalley, Keiran S.M.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679729/
https://ncbi.nlm.nih.gov/pubmed/26073081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.188
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