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Caspase-Dependent Degradation of MDMx/MDM4 Cell Cycle Regulatory Protein in Amyloid β-induced Neuronal Damage

MDMx/MDM4 is a negative regulator of the p53 tumor suppressor protein and is necessary for survival in dividing cells. MDMx is also expressed in postmitotic neurons, with prosurvival roles that are independent of its extensively described roles in carcinogenesis. We and others have shown a role for...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurosci Lett
Päätekijät: Colacurcio, Daniel J., Zyskind, Jacob W., Jordan-Sciutto, Kelly L., Espinoza, Cagla Akay
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679561/
https://ncbi.nlm.nih.gov/pubmed/26477779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.10.031
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