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Calpain-mediated degradation of MDMx/MDM4 contributes to HIV-induced neuronal damage

Neuronal damage in HIV-associated Neurocognitive Disorders (HAND) has been linked to inflammation induced by soluble factors released by HIV-infected, and non-infected, activated macrophages/microglia (HIV M/M) in the brain. It has been suggested that aberrant neuronal cell cycle activation determin...

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Detalhes bibliográficos
Main Authors: Colacurcio, Daniel J., Yeager, Alyssa, Kolson, Dennis L., Jordan-Sciutto, Kelly L., Akay, Cagla
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868345/
https://ncbi.nlm.nih.gov/pubmed/24128662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2013.10.003
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