Parallel high throughput neuronal toxicity assays demonstrate uncoupling between loss of mitochondrial membrane potential and neuronal damage in a model of HIV–induced neurodegeneration

Neurocognitive deficits seen in HIV-associated neurocognitive disorders (HAND) are attributed to the release of soluble factors from CNS-resident, HIV-infected and/or activated macrophages and microglia. To study HIV-associated neurotoxicity, we used our in vitro model in which primary rat neuronal/...

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Main Authors: White, Michael G., Wang, Ying, Akay, Cagla, Lindl, Kathryn A., Kolson, Dennis L., Jordan-Sciutto, Kelly L.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091994/
https://ncbi.nlm.nih.gov/pubmed/21291924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neures.2011.01.013
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