E2F1 localizes predominantly to neuronal cytoplasm and fails to induce expression of its transcriptional targets in Human Immunodeficiency Virus-induced neuronal damage

As human immunodeficiency virus (HIV) does not induce neuronal damage by direct infection, the mechanisms of neuronal damage or loss in HIV associated dementia (HAD) remain unclear. We have shown previously that immunoreactivity of transcription factor, E2F1, increases in neurons, localizing predomi...

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Detalhes bibliográficos
Main Authors: Wang, Ying, Shyam, Nikhil, Ting, Jenhao H., Akay, Cagla, Lindl, Kathryn A., Jordan-Sciutto, Kelly L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902623/
https://ncbi.nlm.nih.gov/pubmed/20580656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.05.032
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