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The Breast Cancer Susceptibility Gene Product (γ-Synuclein) Alters Cell Behavior through it Interaction with Phospholipase Cβ
The breast cancer susceptibility gene protein, also known as γ-synuclein, is highly expressed in human breast cancer in a stage-specific manner, with highest expression in late stage cancer. In model systems, γ-synuclein binds phospholipase Cβ2 which is regulated by Gαq to generate intracellular Ca(...
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| Publicado en: | Cell Signal |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679517/ https://ncbi.nlm.nih.gov/pubmed/26521046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.10.018 |
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