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The Breast Cancer Susceptibility Gene Product (γ-Synuclein) Alters Cell Behavior through it Interaction with Phospholipase Cβ

The breast cancer susceptibility gene protein, also known as γ-synuclein, is highly expressed in human breast cancer in a stage-specific manner, with highest expression in late stage cancer. In model systems, γ-synuclein binds phospholipase Cβ2 which is regulated by Gαq to generate intracellular Ca(...

詳細記述

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書誌詳細
出版年:Cell Signal
主要な著者: Yerramilli, V. Siddartha, Scarlata, Suzanne
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679517/
https://ncbi.nlm.nih.gov/pubmed/26521046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.10.018
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