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γ-Synuclein Interacts with Phospholipase Cβ2 to Modulate G Protein Activation

Phospholipase Cβ2 (PLC β2) is activated by G proteins and generates calcium signals in cells. PLCβ2 is absent in normal breast tissue, but is highly expressed in breast tumors where its expression is correlated with the progression and migration of the tumor. This pattern of expression parallels the...

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Detalhes bibliográficos
Main Authors: Golebiewska, Urszula, Guo, Yuanjian, Khalikaprasad, Narindra, Zurawsky, Cassandra, Yerramilli, V. Siddhartha, Scarlata, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414502/
https://ncbi.nlm.nih.gov/pubmed/22905097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041067
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